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    The Effect

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    Actress and singer Billie Piper makes her debut at the National Theatre this autumn in this "clinical romance" by Enron playwright Lucy Prebble. The Effect is a drama on sanity, neurology, love and the limits of medicine, and reunites Prebble with director Rupert Goold, who was also at the helm in Enron - the award-winning play based on the 2001 scandal that led to the bankruptcy of the major American energy company. Piper (who cut her acting teeth with Doctor Who and starred in ITV's critically acclaimed Secret Diary of a Call Girl, which was also written by Prebble) was last seen on the stage in Neil LaBute's Reasons to be Pretty at the Almeida, in which BBC Radio 4 described her as "fantastic, completely brilliant". Both funny and moving, this vibrant theatrical exploration into the human brain via the human heart also stars Tom Goodman-Hill, Anastasia Hille and Jonjo O'Neill.

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